Protein FAM81B (FAM81B)

About Protein FAM81B

Protein FAM81B (FAM81B) is a protein from Homo sapiens identified by UniProt accession Q96LP2, 452 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein name	Protein FAM81B
UniProt accession	Q96LP2
Gene	FAM81B
Organism	Homo sapiens
Length	452 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (13)

Diseases linked to this target (Open Targets).

ependymoma · score 0.04
metabolite measurement · score 0.04
central nervous system cancer · score 0.03
amyloid-beta measurement · score 0.02
nasopharyngeal neoplasm · score 0.02
Tetralogy of Fallot · score 0.02
Abnormal sperm morphology · score 0.02
IGA glomerulonephritis · score 0.01
endometrial carcinoma · score 0.01
non-small cell lung carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96LP2-F1	alphafold	PREDICTED	75.62	—

Amino-acid sequence (452 residues)

MQLQFLGTLA SSEKRKKSQR LFFKNIKSTK NKAGKASIMS SDTNVNKSAS PTATAEEQPV EPDGPLPGSD NNQEKKVRLS PAKMSTKNST DLVEYVDKSH AFLPIIPNTQ RGQLEDRLNN QARTIAFLLE QAFRIKEDIS ACLQGTHGFR KEESLARKLL ESHIQTITSI VKKLSQNIEI LEDQIRARDQ AATGTNFAVH EINIKHLQGV GDLRGRVARC DSSIVKLSGD IHLFRQEHRQ IEKAIQEFVP ALETLSKNLD MKVMQLLGKI ETASSEQTSN LKMVQGDYRH EMNLLEFKFH SLSSNLYEEV ENNKKWTENQ FLKYRKDHLG HINECLKVLQ EKLEKSENKM EEKLLQLSSK VENFINTQKQ ETQLSKVKHM ENKLSKKMEQ MEKQIWGELE TMQNEYQSGF KSIHDSLSSL QQIQKTKMDL EKYKVQKDLK KLQRKIVELQ EV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards