About Uncharacterized protein C12orf42
Uncharacterized protein C12orf42 (C12orf42) is a protein
from Homo sapiens identified by UniProt accession
Q96LP6, 360 residues long.
MolForge cross-references it against 0 known binders and
38 disease associations.
Target properties
| Protein name | Uncharacterized protein C12orf42 |
| UniProt accession | Q96LP6 |
| Gene | C12orf42 |
| Organism | Homo sapiens |
| Length | 360 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- body mass index · score 0.47
- lean body mass · score 0.46
- fat body mass · score 0.42
- body fat percentage · score 0.40
- hypothyroidism · score 0.40
- Thyroid preparation use measurement · score 0.38
- body weight · score 0.37
- systemic lupus erythematosus · score 0.33
- body height · score 0.31
- autoimmune disease · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q96LP6-F1 | alphafold | PREDICTED | 44.25 | — |
Amino-acid sequence (360 residues)
MSTVICMKQR EEEFLLTIRP FANRMQKSPC YIPIVSSATL WDRSTPSAKH IPCYERTSVP CSRFINHMKN FSESPKFRSL HFLNFPVFPE RTQNSMACKR LLHTCQYIVP RCSVSTVSFD EESYEEFRSS PAPSSETDEA PLIFTARGET EERARGAPKQ AWNSSFLEQL VKKPNWAHSV NPVHLEAQGI HISRHTRPKG QPLSSPKKNS GSAARPSTAI GLCRRSQTPG ALQSTGPSNT ELEPEERMAV PAGAQAHPDD IQSRLLGASG NPVGKGAVAM APEMLPKHPH TPRDRRPQAD TSLHGNLAGA PLPLLAGAST HFPSKRLIKV CSSAPPRPTR RFHTVCSQAL SRPVVNAHLH
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