About Chemokine-like protein TAFA-4
Chemokine-like protein TAFA-4 (TAFA4) is a protein
from Homo sapiens identified by UniProt accession
Q96LR4, 140 residues long.
MolForge cross-references it against 0 known binders and
51 disease associations.
Target properties
| Protein name | Chemokine-like protein TAFA-4 |
|---|
| UniProt accession | Q96LR4 |
|---|
| Gene | TAFA4 |
|---|
| Organism | Homo sapiens |
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| Length | 140 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (51)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.38
- refractive error measurement · score 0.38
- Abnormality of refraction · score 0.31
- refractive error · score 0.30
- neuroticism measurement · score 0.29
- Chest pain · score 0.28
- hemoglobin E-beta-thalassemia syndrome · score 0.06
- primary familial polycythemia due to EPO receptor mutation · score 0.05
- Adult-onset autosomal recessive sideroblastic anemia · score 0.05
- hemolytic anemia due to diphosphoglycerate mutase deficiency · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96LR4-F1 | alphafold | PREDICTED | 85.73 | — |
Amino-acid sequence (140 residues)
MRSPRMRVCA KSVLLSHWLF LAYVLMVCCK LMSASSQHLR GHAGHHQIKQ GTCEVVAVHR CCNKNRIEER SQTVKCSCFP GQVAGTTRAQ PSCVEASIVI QKWWCHMNPC LEGEDCKVLP DYSGWSCSSG NKVKTTKVTR
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