About Mitochondrial inner membrane protease subunit 1
Mitochondrial inner membrane protease subunit 1 (IMMP1L) is a protein
from Homo sapiens identified by UniProt accession
Q96LU5, 166 residues long.
MolForge cross-references it against 0 known binders and
22 disease associations.
Target properties
| Protein name | Mitochondrial inner membrane protease subunit 1 |
|---|
| UniProt accession | Q96LU5 |
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| Gene | IMMP1L |
|---|
| Organism | Homo sapiens |
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| Length | 166 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (22)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- isolated aniridia · score 0.33
- aniridia · score 0.33
- optic disc area measurement · score 0.14
- macula measurement · score 0.12
- health study participation · score 0.11
- cup-to-disc ratio measurement · score 0.11
- optic disc size measurement · score 0.10
- refractive error measurement · score 0.10
- cortical surface area measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96LU5-F1 | alphafold | PREDICTED | 88.08 | — |
Amino-acid sequence (166 residues)
MLRGVLGKTF RLVGYTIQYG CIAHCAFEYV GGVVMCSGPS MEPTIQNSDI VFAENLSRHF YGIQRGDIVI AKSPSDPKSN ICKRVIGLEG DKILTTSPSD FFKSHSYVPM GHVWLEGDNL QNSTDSRCYG PIPYGLIRGR IFFKIWPLSD FGFLRASPNG HRFSDD
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