Ribosomal protein S6 kinase-related protein (RSKR)

About Ribosomal protein S6 kinase-related protein

Ribosomal protein S6 kinase-related protein (RSKR) is a protein from Homo sapiens identified by UniProt accession Q96LW2, 410 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	Ribosomal protein S6 kinase-related protein
UniProt accession	Q96LW2
Gene	RSKR
Organism	Homo sapiens
Length	410 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (11)

Diseases linked to this target (Open Targets).

insomnia measurement · score 0.06
ependymoma · score 0.01
astrocytoma · score 0.01
diabetes mellitus · score 0.01
clear cell renal carcinoma · score 0.01
tuberculosis · score 0.00
invasive breast ductal carcinoma · score 0.00
progressive supranuclear palsy · score 0.00
lung adenocarcinoma · score 0.00
type 2 diabetes mellitus · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96LW2-F1	alphafold	PREDICTED	75.79	—

Amino-acid sequence (410 residues)

MGAVSCRQGQ HTQQGEHTRV AVPHKQGGNI RGPWARGWKS LWTGLGTIRS DLEELWELRG HHYLHQESLK PAPVLVEKPL PEWPVPQFIN LFLPEFPIRP IRGQQQLKIL GLVAKGSFGT VLKVLDCTQK AVFAVKVVPK VKVLQRDTVR QCKEEVSIQR QINHPFVHSL GDSWQGKRHL FIMCSYCSTD LYSLWSAVGC FPEASIRLFA AELVLVLCYL HDLGIMHRDV KMENILLDER GHLKLTDFGL SRHVPQGAQA YTICGTLQYM APEVLSGGPY NHAADWWSLG VLLFSLATGK FPVAAERDHV AMLASVTHSD SEIPASLNQG LSLLLHELLC QNPLHRLRYL HHFQVHPFFR GVAFDPELLQ KQPVNFVTET QATQPSSAET MPFDDFDCDL ESFLLYPIPA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards