About Tektin-5
Tektin-5 (TEKT5) is a protein
from Homo sapiens identified by UniProt accession
Q96M29, 485 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Tektin-5 |
|---|
| UniProt accession | Q96M29 |
|---|
| Gene | TEKT5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 485 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (16)
Diseases linked to this target (Open Targets).
- FEV/FVC ratio · score 0.45
- diet measurement · score 0.26
- body height · score 0.24
- hair colour measurement · score 0.19
- chronic obstructive pulmonary disease · score 0.10
- peak expiratory flow · score 0.06
- heel bone mineral density · score 0.03
- cancer · score 0.02
- aspartate aminotransferase measurement · score 0.02
- infect · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96M29-F1 | alphafold | PREDICTED | 85.47 | — |
Amino-acid sequence (485 residues)
MEFLGTTQTA SYCGPKKCCG LTSLPAVQAP VIQECYQPYY LPGYRYLNSW RPSLFYKIAN VQTCPDESTS TLRPPTILPT LRSALFSRYS PHDWDQSNQL QVRGAEASRL WASRLTDDSM RLLQDKDQLT HQMQEGTCRN LGQRLSDIGF WKSELSYELD RLLTENQNLE TVKRRLECAA NEVNCPLQVA LECLYHREKR IGIDLVHDNV EKNLIREVDL LKCCQEQMRK LAQRIDIQMR DNRDAQHVLE RDLEDKSSAQ CIDEKCFNLR NTSDCISFFH GMEKIDGTIS VPETWAKFSN DNIKHSQNMR ANSIQLREEA EHLFETLSDQ MWRQFTDTNL AFNARISEVT DVKNKLQTQL AKTLQEIFQA ENTIMLLERS IMAKEGPLKV AQTRLECRTR RPNMELCRDI PQLKLVNEVF TIDDTLQTLK LRLRETQDTL QLLVMTKCRL EHELAIKANT LCIDKEKCMG MRKTFPCTPR LVGHT
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