NBPF family member NBPF4 (NBPF4)

About NBPF family member NBPF4

NBPF family member NBPF4 (NBPF4) is a protein from Homo sapiens identified by UniProt accession Q96M43, 638 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	NBPF family member NBPF4
UniProt accession	Q96M43
Gene	NBPF4
Organism	Homo sapiens
Length	638 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

neutrophil count · score 0.07
hemoglobin A1 measurement · score 0.04
mean corpuscular volume · score 0.03
HbA1c measurement · score 0.03
sum of basophil and neutrophil counts · score 0.03
neoplasm · score 0.01
osteosarcoma · score 0.01
colorectal cancer · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96M43-F1	alphafold	PREDICTED	49.83	—

Amino-acid sequence (638 residues)

MVVSADPLSS ERAEMNILEI NQELRSQLAE SNQQFRDLKE KFLITQATAY SLANQLKKYK CEEYKDIIDS VLRDELQSME KLAEKLRQAE ELRQYKALVH SQAKELTQLR EKLREGRDAS RWLNKHLKTL LTPDDPDKSQ GQDLREQLAE GHRLAEHLVH KLSPENDEDE DEDEDDKDEE VEKVQESPAP REVQKTEEKE VPQDSLEECA VTCSNSHNPS NSNQPHRSTK ITFKEHEVDS ALVVESEHPH DEEEEALNIP PENQNDHEEE EGKAPVPPRH HDKSNSYRHR EVSFLALDEQ KVCSAQDVAR DYSNPKWDET SLGFLEKQSD LEEVKGQETV APRLSRGPLR VDKHEIPQES LDGCCLTPSI LPDLTPSYHP YWSTLYSFED KQVSLALVDK IKKDQEEIED QSPPCPRLSQ ELPEVKEQEV PEDSVNEVYL TPSVHHDVSD CHQPYSSTLS SLEDQLACSA LDVASPTEAA CPQGTWSGDL SHHQSEVQVS QAQLEPSTLV PSCLRLQLDQ GFHCGNGLAQ RGLSSTTCSF SANADSGNQW PFQELVLEPS LGMKNPPQLE DDALEGSASN TQGRQVTGRI RASLVLILKT IRRRLPFSKW RLAFRFAGPH AESAEIPNTA GRTQRMAG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards