Protein TBATA (TBATA)

Homo sapiens — UniProt Q96M53

Gene: TBATAHomo sapiensSwissProt reviewed

About Protein TBATA

Protein TBATA (TBATA) is a protein from Homo sapiens identified by UniProt accession Q96M53, 351 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein nameProtein TBATA
UniProt accessionQ96M53
GeneTBATA
OrganismHomo sapiens
Length351 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (19)

Diseases linked to this target (Open Targets).

  • Hirschsprung disease · score 0.29
  • drug use measurement · score 0.21
  • heel bone mineral density · score 0.12
  • Aganglionic megacolon · score 0.11
  • Red cell distribution width · score 0.09
  • optic disc size measurement · score 0.08
  • short-limb skeletal dysplasia with severe combined immunodeficiency · score 0.04
  • reticular dysgenesis · score 0.04
  • metabolite measurement · score 0.03
  • smoking status measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96M53-F1alphafoldPREDICTED60.55—

Amino-acid sequence (351 residues)

MATDVQLADY PLMSPKAELK LEKKSGRKPR SPRDSGPQKE LVIPGIVDFE RIRRALRTPK PQTPGTYCFG RLSHHSFFSR HHPHPQHVTH IQDLTGKPVC VVRDFPAPLP ESTVFSGCQM GIPTISVPIG DPQSNRNPQL SSEAWKKELK ELASRVAFLT KEDELKKKEK EQKEEPLREQ GAKYSAETGR LIPASTRAVG RRRSHQGQQS QSSSRHEGVQ AFLLQDQELL VLELLCRILE TDLLSAIQFW LLYAPPKEKD LALGLLQTAV AQLLPQPLVS IPTEKLLSQL PEVHEPPQEK QEPPCSQSPK KTKISPFTKS EKPEYIGEAQ VLQMHSSQNT EKKTSKPRAE S

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Quick facts

UniProtQ96M53
GeneTBATA
OrganismHomo sapiens
Length351
Binders0
Diseases19
View on UniProt