About Outer dynein arm-docking complex subunit 1
Outer dynein arm-docking complex subunit 1 (ODAD1) is a protein
from Homo sapiens identified by UniProt accession
Q96M63, 670 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Outer dynein arm-docking complex subunit 1 |
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| UniProt accession | Q96M63 |
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| Gene | ODAD1 |
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| Organism | Homo sapiens |
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| Length | 670 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (30)
Diseases linked to this target (Open Targets).
- primary ciliary dyskinesia · score 0.72
- protein measurement · score 0.14
- sitting height measurement · score 0.13
- Fraser syndrome · score 0.11
- platelet crit · score 0.11
- platelet count · score 0.07
- psoriasis · score 0.02
- nasopharyngeal neoplasm · score 0.02
- situs inversus · score 0.01
- kidney disease · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96M63-F1 | alphafold | PREDICTED | 71.32 | — |
Amino-acid sequence (670 residues)
MEGERRAYSK EVHQRINKQL EEIRRLEEVR GDLQVQISAA QNQVKRLRDS QRLENMDRLL KGRAQVQAEI EELQEQTRAL DKQIQEWETR IFTHSKNVRS PGFILDQKVK IRRRIRILEN QLDRVTCHFD NQLVRNAALR EELDLLRIDR NRYLNVDRKL KKEIHHLHHL VSTLILSSTS AYAVREEAKA KMGLLRERAE KEEAQSEMEA QVLQRQILHL EQLHHFLKLK NNDRQPDPDV LEKREKQAGE VAEGVWKTSQ ERLVLCYEDA LNKLSQLMGE SDPDLLVQKY LEIEERNFAE FNFINEQNLE LEHVQEEIKE MQEALVSARA SKDDQHLLQE QQQKVLQQRM DKVHSEAERL EARFQDVRGQ LEKLKADIQL LFTKAHCDSS MIDDLLGVKT SMGDRDMGLF LSLIEKRLVE LLTVQAFLHA QSFTSLADAA LLVLGQSLED LPKKMAPLQP PDTLEDPPGF EASDDYPMSR EELLSQVEKL VELQEQAEAQ RQKDLAAAAA KLDGTLSVDL ASTQRAGSST VLVPTRHPHA IPGSILSHKT SRDRGSLGHV TFGGLSSSTG HLPSHITHGD PNTGHVTFGS TSASSGGHVT FRPVSASSYL GSTGYVGSSR GGENTEGGVE SGGTASDSSG GLGSSRDHVS STGPASSTGP GSSTSKDSRG
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