About CEP295 N-terminal-like protein
CEP295 N-terminal-like protein (CEP295NL) is a protein
from Homo sapiens identified by UniProt accession
Q96MC4, 621 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | CEP295 N-terminal-like protein |
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| UniProt accession | Q96MC4 |
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| Gene | CEP295NL |
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| Organism | Homo sapiens |
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| Length | 621 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (23)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.38
- gut microbiome measurement · score 0.30
- hip bone mineral density · score 0.28
- hip bone size · score 0.28
- heel bone mineral density · score 0.27
- respiratory system disease · score 0.19
- waist-hip ratio · score 0.15
- body height · score 0.12
- bone quantitative ultrasound measurement · score 0.11
- BMI-adjusted waist-hip ratio · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96MC4-F1 | alphafold | PREDICTED | 57.82 | — |
Amino-acid sequence (621 residues)
MCSGWSSSVI WRHTQFAVER CGFCGSSGPG APLEPSTLGS KHLPWEAVSA GFADRNRNMD GAMWLSLCPD NEDLLWRKKH KLLQARGKGD LALQRRADAK LWKNYQLQRL AEELRRGYQE AQHLHVGGLD RLQSARLLGW GGGRARENEP DSQGPIQRRS ARPPRAKEKH RAALSEERSC REELGQQHPR HSRPRKTAAS PEKPQTTKAT GRMNSHLAPP EKRKGRPEPS TKSGGGRCAI HPRRSKGADL ERSNPLVAAV GEIGLVEEKE KGTARAGRRQ LGKGAVCFVP ALTSRSQGQS LEGKLRDLGQ LWPADSSCRR EAVSPASQCT LREKNKWQKE LELAFEELFN INRKLKKHLC LYLALKPRMD QRPGEGHAFS EMQECGAGTP RGKKMADPEM LPAGEPRSPA EEEAQQAASK TDLKTFMGKA QNQKYQGTVK PTFRNGSQTL SPEAGIFINK EDSLLYSTES GQETPKLGTL AEGSLQLHLQ DQADRVGSTA SRQRQKAEME QRRQKQLESL EQMEHPDMSL EIHYKAELEK ERREQRRARL AHLKSSSTRA QERERGSELS TTSPSGTSLA DDDRHSQMIR DQQQQILQQN RLHKQFLEEA RKCLREFQNI C
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