About Solute carrier family 71 member 1
Solute carrier family 71 member 1 (SLC71A1) is a protein
from Homo sapiens identified by UniProt accession
Q96MC6, 490 residues long.
MolForge cross-references it against 0 known binders and
93 disease associations.
Target properties
| Protein name | Solute carrier family 71 member 1 |
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| UniProt accession | Q96MC6 |
|---|
| Gene | SLC71A1 |
|---|
| Organism | Homo sapiens |
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| Length | 490 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (93)
Diseases linked to this target (Open Targets).
- bipolar II disorder · score 0.13
- azoospermia · score 0.09
- male infertility with teratozoospermia due to single gene mutation · score 0.08
- partial chromosome Y deletion · score 0.07
- gut microbiome measurement · score 0.07
- congenital bilateral absence of vas deferens · score 0.06
- spermatogenic failure 39 · score 0.06
- spermatogenic failure, X-linked, 3 · score 0.06
- spermatogenic failure 65 · score 0.06
- spermatogenic failure 51 · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96MC6-F1 | alphafold | PREDICTED | 78.97 | — |
Amino-acid sequence (490 residues)
MTQGKKKKRA ANRSIMLAKK IIIKDGGTPQ GIGSPSVYHA VIVIFLEFFA WGLLTAPTLV VLHETFPKHT FLMNGLIQGV KGLLSFLSAP LIGALSDVWG RKSFLLLTVF FTCAPIPLMK ISPWWYFAVI SVSGVFAVTF SVVFAYVADI TQEHERSMAY GLVSATFAAS LVTSPAIGAY LGRVYGDSLV VVLATAIALL DICFILVAVP ESLPEKMRPA SWGAPISWEQ ADPFASLKKV GQDSIVLLIC ITVFLSYLPE AGQYSSFFLY LRQIMKFSPE SVAAFIAVLG ILSIIAQTIV LSLLMRSIGN KNTILLGLGF QILQLAWYGF GSEPWMMWAA GAVAAMSSIT FPAVSALVSR TADADQQGVV QGMITGIRGL CNGLGPALYG FIFYIFHVEL KELPITGTDL GTNTSPQHHF EQNSIIPGPP FLFGACSVLL ALLVALFIPE HTNLSLRSSS WRKHCGSHSH PHNTQAPGEA KEPLLQDTNV
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