About Zinc finger protein 512
Zinc finger protein 512 (ZNF512) is a protein
from Homo sapiens identified by UniProt accession
Q96ME7, 567 residues long.
MolForge cross-references it against 0 known binders and
52 disease associations.
Target properties
| Protein name | Zinc finger protein 512 |
|---|
| UniProt accession | Q96ME7 |
|---|
| Gene | ZNF512 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 567 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (52)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.28
- erythrocyte count · score 0.27
- very low density lipoprotein cholesterol measurement · score 0.26
- phospholipid measurement · score 0.25
- chylomicron measurement · score 0.24
- metabolic syndrome · score 0.22
- total cholesterol measurement · score 0.18
- type 2 diabetes mellitus · score 0.17
- prostate carcinoma · score 0.17
- self reported educational attainment · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96ME7-F1 | alphafold | PREDICTED | 62.51 | — |
Amino-acid sequence (567 residues)
MSSRLGAVPA TSGPTTFKQQ RSTRIVGAKN SRTQCSIKDN SFQYTIPHDD SLSGSSSASS CEPVSDFPAS FRKSTYWMKM RRIKPAATSH VEGSGGVSAK GKRKPRQEED EDYREFPQKK HKLYGRKQRP KTQPNPKSQA RRIRKEPPVY AAGSLEEQWY LEIVDKGSVS CPTCQAVGRK TIEGLKKHME NCKQEMFTCH HCGKQLRSLA GMKYHVMANH NSLPILKAGD EIDEPSERER LRTVLKRLGK LRCMRESCSS SFTSIMGYLY HVRKCGKGAA ELEKMTLKCH HCGKPYRSKA GLAYHLRSEH GPISFFPESG QPECLKEMNL ESKSGGRVQR RSAKIAVYHL QELASAELAK EWPKRKVLQD LVPDDRKLKY TRPGLPTFSQ EVLHKWKTDI KKYHRIQCPN QGCEAVYSSV SGLKAHLGSC TLGNFVAGKY KCLLCQKEFV SESGVKYHIN SVHAEDWFVV NPTTTKSFEK LMKIKQRQQE EEKRRQQHRS RRSLRRRQQP GIELPETELS LRVGKDQRRN NEELVVSASC KEPEQEPVPA QFQKVKPPKT NHKRGRK
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