About Protein HEXIM2
Protein HEXIM2 (HEXIM2) is a protein
from Homo sapiens identified by UniProt accession
Q96MH2, 286 residues long.
MolForge cross-references it against 0 known binders and
28 disease associations.
Target properties
| Protein name | Protein HEXIM2 |
|---|
| UniProt accession | Q96MH2 |
|---|
| Gene | HEXIM2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 286 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (28)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.29
- insomnia measurement · score 0.28
- refractive error measurement · score 0.27
- neurodegenerative disease · score 0.24
- balding measurement · score 0.22
- eosinophil percentage of leukocytes · score 0.07
- fat body mass · score 0.07
- hypertension · score 0.06
- systolic blood pressure · score 0.05
- base metabolic rate measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96MH2-F1 | alphafold | PREDICTED | 70.30 | — |
Amino-acid sequence (286 residues)
MMATPNQTAC NAESPVALEE AKTSGAPGSP QTPPERHDSG GSLPLTPRME SHSEDEDLAG AVGGLGWNSR SPRTQSPGGC SAEAVLARKK HRRRPSKRKR HWRPYLELSW AEKQQRDERQ SQRASRVREE MFAKGQPVAP YNTTQFLMND RDPEEPNLDV PHGISHPGSS GESEAGDSDG RGRAHGEFQR KDFSETYERF HTESLQGRSK QELVRDYLEL EKRLSQAEEE TRRLQQLQAC TGQQSCRQVE ELAAEVQRLR TENQRLRQEN QMWNREGCRC DEEPGT
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