About RIPOR family member 3
RIPOR family member 3 (RIPOR3) is a protein
from Homo sapiens identified by UniProt accession
Q96MK2, 946 residues long.
MolForge cross-references it against 0 known binders and
75 disease associations.
Target properties
| Protein name | RIPOR family member 3 |
|---|
| UniProt accession | Q96MK2 |
|---|
| Gene | RIPOR3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 946 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (75)
Diseases linked to this target (Open Targets).
- bone density · score 0.32
- urate measurement · score 0.32
- platelet component distribution width · score 0.32
- neutrophil count · score 0.31
- leukocyte count · score 0.28
- mean corpuscular hemoglobin concentration · score 0.26
- hemoglobin measurement · score 0.26
- lymphocyte count · score 0.22
- mean reticulocyte volume · score 0.16
- erythrocyte count · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96MK2-F1 | alphafold | PREDICTED | 68.71 | — |
Amino-acid sequence (946 residues)
MSVRLRFLSP GDTGAVGVVG RSASFAGFSS AQSRRIAKSI NRNSVRSRMP AKSSKMYGTL RKGSVCADPK PQQVKKIFEA LKRGLKEYLC VQQAELDHLS GRHKDTRRNS RLAFYYDLDK QTRCVERHIR KMEFHISKVD ELYEDYCIQC RLRDGASSMQ RAFARCPPSR AARESLQELG RSLHECAEDM WLIEGALEVH LGEFHIRMKG LVGYARLCPG DHYEVLMRLG RQRWKLKGRI ESDDSQTWDE EEKAFIPTLH ENLDIKVTEL RGLGSLAVGA VTCDIADFFT TRPQVIVVDI TELGTIKLQL EVQWNPFDTE SFLVSPSPTG KFSMGSRKGS LYNWTPPSTP SFRERYYLSV LQQPTQQALL LGGPRATSIL SYLSDSDLRG PSLRSQSQEL PEMDSFSSED PRDTETSTSA STSDVGFLPL TFGPHASIEE EAREDPLPPG LLPEMAHLSG GPFAEQPGWR NLGGESPSLP QGSLFHSGTA SSSQNGHEEG ATGDREDGPG VALEGPLQEV LELLRPTDST QPQLRELEYQ VLGFRDRLKP CRARQEHTSA ESLMECILES FAFLNADFAL DELSLFGGSQ GLRKDRPLPP PSSLKASSRE LTAGAPELDV LLMVHLQVCK ALLQKLASPN LSRLVQECLL EEVAQQKHVL ETLSVLDFEK VGKATSIEEI IPQASRTKGC LKLWRGCTGP GRVLSCPATT LLNQLKKTFQ HRVRGKYPGQ LEIACRRLLE QVVSCGGLLP GAGLPEEQII TWFQFHSYLQ RQSVSDLEKH FTQLTKEVTL IEELHCAGQA KVVRKLQGKR LGQLQPLPQT LRAWALLQLD GTPRVCRAAS ARLAGAVRNR SFREKALLFY TNALAENDAR LQQAACLALK HLKGIESIDQ TASLCQSDLE AVRAAARETT LSFGEKGRLA FEKMDKLCSE QREVFCQEAD VEITIF
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