About Zinc finger protein 42 homolog
Zinc finger protein 42 homolog (ZFP42) is a protein
from Homo sapiens identified by UniProt accession
Q96MM3, 310 residues long.
MolForge cross-references it against 0 known binders and
130 disease associations.
Target properties
| Protein name | Zinc finger protein 42 homolog |
|---|
| UniProt accession | Q96MM3 |
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| Gene | ZFP42 |
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| Organism | Homo sapiens |
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| Length | 310 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (130)
Diseases linked to this target (Open Targets).
- Testicular Germ Cell Tumor · score 0.40
- age at menopause · score 0.33
- menopause · score 0.31
- xanthine measurement · score 0.26
- breast milk measurement · score 0.25
- lysosomal storage disease · score 0.25
- Alzheimer disease · score 0.25
- neurodegenerative disease · score 0.25
- Parkinson disease · score 0.25
- multiple sclerosis · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96MM3-F1 | alphafold | PREDICTED | 56.62 | — |
Amino-acid sequence (310 residues)
MSQQLKKRAK TRHQKGLGGR APSGAKPRQG KSSQDLQAEI EPVSAVWALC DGYVCYEPGP QALGGDDFSD CYIECVIRGE FSQPILEEDS LFESLEYLKK GSEQQLSQKV FEASSLECSL EYMKKGVKKE LPQKIVGENS LEYSEYMTGK KLPPGGIPGI DLSDPKQLAE FARKKPPINK EYDSLSAIAC PQSGCTRKLR NRAALRKHLL IHGPRDHVCA ECGKAFVESS KLKRHFLVHT GEKPFRCTFE GCGKRFSLDF NLRTHVRIHT GEKRFVCPFQ GCNRRFIQSN NLKAHILTHA NTNKNEQEGK
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