About Zinc finger SWIM domain-containing protein 3
Zinc finger SWIM domain-containing protein 3 (ZSWIM3) is a protein
from Homo sapiens identified by UniProt accession
Q96MP5, 696 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Zinc finger SWIM domain-containing protein 3 |
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| UniProt accession | Q96MP5 |
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| Gene | ZSWIM3 |
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| Organism | Homo sapiens |
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| Length | 696 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (8)
Diseases linked to this target (Open Targets).
- body height · score 0.18
- mean platelet volume · score 0.15
- vital capacity · score 0.12
- telomere length · score 0.12
- cancer · score 0.01
- neoplasm · score 0.01
- acute lung injury · score 0.00
- uterine cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96MP5-F1 | alphafold | PREDICTED | 71.38 | — |
Amino-acid sequence (696 residues)
MELGSCFKTY EDFKECFSAY KRENRCSFIL RDCVSVRFHN LNHGTSIRED ILYVQVKFVC IRTQSNRKRT READMCPAYL LLRYNERLDR LFISELNTQH IHGDSKVASP GGDTTGKSQK TMCLQRLQPV QPTTKKDLDT AEKSLVEPSF CLDKVQVSSK PEQEGITPSD LAKIAKVMKN FLKVDEGSMA SFSVGDSQHL DRLSFQSSKM TDLFIRFPEN LLLHRVENTQ GHILYAFLVE NKERESRVVH FAVLKAETVT SVAKMLSIFT EFNSDWPKVK VVFVDPSFHY RAILQEIFPA ARILLSIYHT TRLLEKKLHR SSANPSFKRL MKEALREAVF VTSEASLKNL CQMSQAVLDE DLFNFLQAHW FTCELLWYMH VRKGLLACNT YMDSLDIVTS KVSSLFREQQ SLLDCILCFV DYIDFFNTKG LKNLPTPPPK LKRARPASMP LKSKKAFGIC GESLTSLPAE ETKPDAQQVQ VQQQSQVPPS QVGMLDTLHQ SGSELAYKLC HNEWEVVQNS THLVDMAGSS VDVQLLEDSH QVSKDGCSCS CSFQQWYHLP CRHILALLHT SQQPVGEAMV CRRWQKKYQY LLGPNGELQD RGMVPNTGQP EKQGRNDMIQ DLSRELANLL MQTEGPELEE RYSTLRKIVD IWAGPSQPSE LFQQPGDFKD VGRLPFLWGK QEEGEGFPPA TAVMHY
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