About Glycosyltransferase 1 domain-containing protein 1
Glycosyltransferase 1 domain-containing protein 1 (GLT1D1) is a protein
from Homo sapiens identified by UniProt accession
Q96MS3, 346 residues long.
MolForge cross-references it against 0 known binders and
48 disease associations.
Target properties
| Protein name | Glycosyltransferase 1 domain-containing protein 1 |
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| UniProt accession | Q96MS3 |
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| Gene | GLT1D1 |
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| Organism | Homo sapiens |
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| Length | 346 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (48)
Diseases linked to this target (Open Targets).
- systemic lupus erythematosus · score 0.34
- age at onset · score 0.32
- neurodegenerative disease · score 0.31
- drug use measurement · score 0.24
- blood protein measurement · score 0.07
- gut microbiome measurement · score 0.06
- B-cell non-Hodgkins lymphoma · score 0.05
- sphingomyelin measurement · score 0.05
- depressive symptom measurement · score 0.05
- herpes virus seropositivity · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96MS3-F1 | alphafold | PREDICTED | 95.68 | — |
Amino-acid sequence (346 residues)
MRLLFLAVLR PHTGNAVTAQ RVRAHLEAAG HVCVLKDAFD FESRSEIANL ILAENCEAAL ALHLYRGGRL LQGHRIPFGV IFGGTDVNED ANQAEKNTVM GRVLEEARFA VAFTESMKEM AQAQWPHAKG KVYVQSQGIA TTPNAAFNWN TFLQRSEINQ SADNLHIFLL ICGLRQVKDP LYLVDAFSAW HQEEPNVHLV IVGPEVDPVF TREVKAKVKR AAGVRLIGEM PQEDLHAVVK NCFAVVNSSV SEGMSAAILE AMDLEVPVLA RNIPGNAAVV KHEVTGLLFS NPQEFVHLAK RLVSDPALEK EIVVNGREYV RMYHSWQVER DTYQQLIRKL EGSTED
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