About Tigger transposable element-derived protein 1
Tigger transposable element-derived protein 1 (TIGD1) is a protein
from Homo sapiens identified by UniProt accession
Q96MW7, 591 residues long.
MolForge cross-references it against 0 known binders and
34 disease associations.
Target properties
| Protein name | Tigger transposable element-derived protein 1 |
|---|
| UniProt accession | Q96MW7 |
|---|
| Gene | TIGD1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 591 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (34)
Diseases linked to this target (Open Targets).
- autosomal recessive multiple pterygium syndrome · score 0.48
- lethal multiple pterygium syndrome · score 0.41
- genetic disorder · score 0.19
- body height · score 0.07
- lymphocyte count · score 0.07
- platelet count · score 0.07
- vital capacity · score 0.06
- diet measurement · score 0.06
- mean corpuscular volume · score 0.06
- age at first facial hair · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96MW7-F1 | alphafold | PREDICTED | 78.02 | — |
Amino-acid sequence (591 residues)
MASKCSSERK SRTSLTLNQK LEMIKLSEEG MSKAEIGRRL GLLRQTVSQV VNAKEKFLKE VKSATPMNTR MIRKRNSLIA DMEKVLVVWI EDQTSRNIPL SQSLIQNKAL TLFNSMKAER GVEAAEEKFE ASRGWFMRFK ERSHFHNIKA QGEAASADVE AAASYPEALA KIIDEGGYTK QQIFNVDETA FYWKKMPSRT FIAREEKSVP GFKASKDRLT LLLGANAAGD FKLKPMLIYH SENPRALKNY TKSTLPVLYK WNSKARMTAH LFTAWFTEYF KPTVETYCSE KKIPFKILLL IDNAPSHPRA LMEIYEEINV IFMPANTTSI LQPMDQGVIS TFKSYYLRNT FHKALAAMDS DVSDGSGQSK LKTFWKGFTI LDAIKNIRDS WEEVKLSTLT GVWKKLIPTL IDDYEGFKTS VEEVSADVVE IAKELELEVE PEDVTELLQS HDKTLTDEEL FLMDAQRKWF LEMESTPGED AVNIVEMTTK DLEYYINLVD KAAAGFERID SNFERSSTVG KMLSNSIACY REIFHERKSQ LMRKASPMSY FRKLPQPPQP SAATTLTSQQ PSTSRQDPPP AKRVRLTEGS D
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