Dynein axonemal assembly factor 10 (DNAAF10)

About Dynein axonemal assembly factor 10

Dynein axonemal assembly factor 10 (DNAAF10) is a protein from Homo sapiens identified by UniProt accession Q96MX6, 357 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.

Target properties

Protein name	Dynein axonemal assembly factor 10
UniProt accession	Q96MX6
Gene	DNAAF10
Organism	Homo sapiens
Length	357 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (51)

Diseases linked to this target (Open Targets).

appendicular lean mass · score 0.38
body height · score 0.35
diastolic blood pressure change measurement · score 0.28
response to diuretic · score 0.28
response to vaccine · score 0.26
cytokine measurement · score 0.26
mathematical ability · score 0.18
grip strength measurement · score 0.17
balding measurement · score 0.17
heel bone mineral density · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96MX6-F1	alphafold	PREDICTED	96.60	—

Amino-acid sequence (357 residues)

MSAFEKPQII AHIQKGFNYT VFDCKWVPCS AKFVTMGNFA RGTGVIQLYE IQHGDLKLLR EIEKAKPIKC GTFGATSLQQ RYLATGDFGG NLHIWNLEAP EMPVYSVKGH KEIINAIDGI GGLGIGEGAP EIVTGSRDGT VKVWDPRQKD DPVANMEPVQ GENKRDCWTV AFGNAYNQEE RVVCAGYDNG DIKLFDLRNM ALRWETNIKN GVCSLEFDRK DISMNKLVAT SLEGKFHVFD MRTQHPTKGF ASVSEKAHKS TVWQVRHLPQ NRELFLTAGG AGGLHLWKYE YPIQRSKKDS EGIEMGVAGS VSLLQNVTLS TQPISSLDWS PDKRGLCVCS SFDQTVRVLI VTKLNKI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards