About Protein FAM161B
Protein FAM161B (FAM161B) is a protein
from Homo sapiens identified by UniProt accession
Q96MY7, 647 residues long.
MolForge cross-references it against 0 known binders and
56 disease associations.
Target properties
| Protein name | Protein FAM161B |
|---|
| UniProt accession | Q96MY7 |
|---|
| Gene | FAM161B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 647 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (56)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- genetic disorder · score 0.15
- familial steroid-resistant nephrotic syndrome with sensorineural deafness · score 0.12
- platelet component distribution width · score 0.08
- body height · score 0.07
- mean corpuscular volume · score 0.07
- protein measurement · score 0.05
- Hepatic veno-occlusive disease - immunodeficiency · score 0.05
- birth weight · score 0.04
- Red cell distribution width · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96MY7-F1 | alphafold | PREDICTED | 67.37 | — |
Amino-acid sequence (647 residues)
MTVGRPEGAP GGAEGSRQIF PPESFADTEA GEELSGDGLV LPRASKLDEF LSPEEEIDST SDSTGSIYQN LQELKQKGRW CLLESLFQSD PESDENLSED EEDLESFFQD KDRGMVQVQC PQALRCGSTR RCSSLNNLPS NIPRPQTQPP SGSRPPSQHR SVSSWASSIT VPRPFRMTLR EARKKAEWLG SPASFEQERQ RAQRQGEEEA ECHRQFRAQP VPAHVYLPLY QEIMERSEAR RQAGIQKRKE LLLSSLKPFS FLEKEEQLKE AARQRDLAAT AEAKISKQKA TRRIPKSILE PALGDKLQEA ELFRKIRIQM RALDMLQMAS SPIASSSNRA NPQPRTATRT QQEKLGFLHT NFRFQPRVNP VVPDYEGLYK AFQRRAAKRR ETQEATRNKP FLLRTANLRH PQRPCDAATT GRRQDSPQPP ATPLPRSRSL SGLASLSANT LPVHITDATR KRESAVRSAL EKKNKADESI QWLEIHKKKS QAMSKSVTLR AKAMDPHKSL EEVFKAKLKE NRNNDRKRAK EYKKELEEMK QRIQTRPYLF EQVAKDLAKK EAEQWYLDTL KQAGLEEDFV RNKGQGTRAV QEKETKIKDF PRFQETTKLS IRDPEQGLEG SLEQPASPRK VLEELSHQSP ENLVSLA
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