V-set and transmembrane domain-containing protein…

About V-set and transmembrane domain-containing protein 2-like protein

V-set and transmembrane domain-containing protein 2-like protein (VSTM2L) is a protein from Homo sapiens identified by UniProt accession Q96N03, 204 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

Target properties

Protein name	V-set and transmembrane domain-containing protein 2-like protein
UniProt accession	Q96N03
Gene	VSTM2L
Organism	Homo sapiens
Length	204 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (31)

Diseases linked to this target (Open Targets).

body mass index · score 0.40
cancer · score 0.08
neoplasm · score 0.04
gastric adenocarcinoma · score 0.03
glioblastoma multiforme · score 0.03
hair colour measurement · score 0.03
Tetralogy of Fallot · score 0.03
cholangiocarcinoma · score 0.02
medulloblastoma · score 0.02
Ataxia-telangiectasia · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96N03-F1	alphafold	PREDICTED	73.25	—

Amino-acid sequence (204 residues)

MGAPLAVALG ALHYLALFLQ LGGATRPAGH APWDNHVSGH ALFTETPHDM TARTGEDVEM ACSFRGSGSP SYSLEIQWWY VRSHRDWTDK QAWASNQLKA SQQEDAGKEA TKISVVKVVG SNISHKLRLS RVKPTDEGTY ECRVIDFSDG KARHHKVKAY LRVQPGENSV LHLPEAPPAA PAPPPPKPGK ELRKRSVDQE ACSL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

V-set and transmembrane domain-containing protein 2-like protein (VSTM2L)