About Zinc finger protein 75A
Zinc finger protein 75A (ZNF75A) is a protein
from Homo sapiens identified by UniProt accession
Q96N20, 296 residues long.
MolForge cross-references it against 0 known binders and
15 disease associations.
Target properties
| Protein name | Zinc finger protein 75A |
| UniProt accession | Q96N20 |
| Gene | ZNF75A |
| Organism | Homo sapiens |
| Length | 296 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- vital capacity · score 0.23
- attention deficit hyperactivity disorder · score 0.21
- antisocial behaviour measurement · score 0.21
- substance abuse · score 0.21
- IGF-1 measurement · score 0.14
- diastolic blood pressure · score 0.09
- serum gamma-glutamyl transferase measurement · score 0.09
- serum alanine aminotransferase measurement · score 0.07
- Genetic renal or urinary tract malformation · score 0.05
- Cystic Kidney Disease · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q96N20-F1 | alphafold | PREDICTED | 73.55 | — |
Amino-acid sequence (296 residues)
MYFSQEEWEL LDPTQKALYN DVMQENYETV ISLALFVLPK PKVISCLEQG EEPWVQVSPE FKDSAGKSPT GLKLKNDTEN HQPVSLSDLE IQASAGVISK KAKVKVPQKT AGKENHFDMH RVGKWHQDFP VKKRKKLSTW KQELLKLMDR HKKDCAREKP FKCQECGKTF RVSSDLIKHQ RIHTEEKPYK CQQCDKRFRW SSDLNKHLTT HQGIKPYKCS WCGKSFSQNT NLHTHQRTHT GEKPFTCHEC GKKFSQNSHL IKHRRTHTGE QPYTCSICRR NFSRRSSLLR HQKLHL
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