Zinc finger protein 578 (ZNF578)

About Zinc finger protein 578

Zinc finger protein 578 (ZNF578) is a protein from Homo sapiens identified by UniProt accession Q96N58, 590 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Zinc finger protein 578
UniProt accession	Q96N58
Gene	ZNF578
Organism	Homo sapiens
Length	590 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

vitamin D measurement · score 0.05
Down syndrome · score 0.04
Ataxia-telangiectasia · score 0.01
Leishmaniasis · score 0.01
Sepsis · score 0.00
neoplasm · score 0.00
cancer · score 0.00
Crohn's disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96N58-F1	alphafold	PREDICTED	65.01	—

Amino-acid sequence (590 residues)

MLHEEAAQKR KGKEPGMALP QGRLTFRDVA IEFSLAEWKF LNPAQRALYR EVMLENYRNL EAVDISSKRM MKEVLSTGQG NTEVIHTGML QRHESYHTGD FCFQEIEKDI HDFEFQSQKD ERNGHEASMP KIKELMGSTD RHDQRHAGNK PIKDQLGLSF HLHLPELHIF QPEEKIANQV EKSVNDASSI STSQRISCRP ETHTPNNYGN NFFHSSLLTQ KQEVHMREKS FQCNETGEAF NCSSFVRKHQ IIHLGEKQYK FDICGKVFNE KRYLARHRRC HTSEKPYKCN ECGKSFSYKS SLTCHRRCHT GEKPYKCNEC GKSFSYKSSL TCHHRCHTGE KPYKCNECGK SFSYKSSLRC HRRLHTGIKP YKCNECGKMF GQNSTLVIHK AIHTGEKPYK CNECGKAFNQ QSHLSRHHRL HTGEKPYKCN DCGKAFIHQS SLARHHRLHT GEKSYKCEEC DRVFSQKSNL ERHKIIHTGE KPYKCNECHK TFSHRSSLPC HRRLHSGEKP YKCNECGKTF NVQSHLSRHH RLHTGEKPYK CKVCDKAFMC HSYLANHTRI HSGEKPYKCN ECGKAHNHLI DSSIKPCMSS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards