Zinc finger protein 641 (ZNF641)

About Zinc finger protein 641

Zinc finger protein 641 (ZNF641) is a protein from Homo sapiens identified by UniProt accession Q96N77, 438 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.

Target properties

Protein name	Zinc finger protein 641
UniProt accession	Q96N77
Gene	ZNF641
Organism	Homo sapiens
Length	438 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (67)

Diseases linked to this target (Open Targets).

glomerular filtration rate · score 0.36
hematocrit · score 0.29
creatinine measurement · score 0.29
neurodegenerative disease · score 0.28
hemoglobin measurement · score 0.26
sitting height measurement · score 0.25
erythrocyte count · score 0.24
bilirubin measurement · score 0.23
systolic blood pressure · score 0.20
type 2 diabetes mellitus · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96N77-F1	alphafold	PREDICTED	48.82	—

Amino-acid sequence (438 residues)

MQAEDRSQFG SAAEMLSEQT AALGTGWESM NVQLDGAEPQ VERGSQEERP WRTVPGPLEH LCCDLEEEPQ SLQEKAQSAP WVPAIPQEGN TGDWEMAAAL LAAGSQGLVT IKDVSLCFSQ EEWRSLDPSQ TDFYGEYVMQ ENCGIVVSLR FPIPKLDMLS QLEGGEEQWV PDPQDLEERD ILRVTYTGDG SEHEGDTPEL EAEPPRMLSS VSEDTVLWNP EHDESWDSMP SSSRGMLLGP PFLQEDSFSN LLCSTEMDSL LRPHTCPQCG KQFVWGSHLA RHQQTHTGER PYSCLKCEKT FGRRHHLIRH QKTHLHDKTS RCSECGKNFR CNSHLASHQR VHAEGKSCKG QEVGESPGTR KRQRAPPVPK CHVCTECGKS FGRRHHLVRH WLTHTGEKPF QCPRCEKSFG RKHHLDRHLL THQGQSPRNS WDRGTSVF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards