About Spermatogenesis-associated protein 13
Spermatogenesis-associated protein 13 (SPATA13) is a protein
from Homo sapiens identified by UniProt accession
Q96N96, 652 residues long.
MolForge cross-references it against 0 known binders and
43 disease associations.
Target properties
| Protein name | Spermatogenesis-associated protein 13 |
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| UniProt accession | Q96N96 |
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| Gene | SPATA13 |
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| Organism | Homo sapiens |
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| Length | 652 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (43)
Diseases linked to this target (Open Targets).
- hypothyroidism · score 0.34
- cerebrospinal fluid biomarker measurement · score 0.29
- thyroid disease · score 0.29
- PHF-tau measurement · score 0.28
- myxedema · score 0.27
- autoimmune disease · score 0.26
- Hashimoto's thyroiditis · score 0.25
- Thyroid preparation use measurement · score 0.25
- endocrine system disease · score 0.24
- heel bone mineral density · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96N96-F1 | alphafold | PREDICTED | 71.68 | — |
Amino-acid sequence (652 residues)
MTSASPEDQN APVGCPKGAR RRRPISVIGG VSLYGTNQTE ELDNLLTQPA SRPPMPAHQV PPYKAVSARF RPFTFSQSTP IGLDRVGRRR QMRASNVSSD GGTEPSALVD DNGSEEDFSY EDLCQASPRY LQPGGEQLAI NELISDGNVV CAEALWDHVT MDDQELGFKA GDVIQVLEAS NKDWWWGRSE DKEAWFPASF VRLRVNQEEL SENSSSTPSE EQDEEASQSR HRHCENKQQM RTNVIREIMD TERVYIKHLR DICEGYIRQC RKHTGMFTVA QLATIFGNIE DIYKFQRKFL KDLEKQYNKE EPHLSEIGSC FLQNQEGFAI YSEYCNNHPG ACLELANLMK QGKYRHFFEA CRLLQQMIDI AIDGFLLTPV QKICKYPLQL AELLKYTTQE HGDYSNIKAA YEAMKNVACL INERKRKLES IDKIARWQVS IVGWEGLDIL DRSSELIHSG ELTKITKQGK SQQRTFFLFD HQLVSCKKDL LRRDMLYYKG RLDMDEMELV DLGDGRDKDC NLSVKNAFKL VSRTTDEVYL FCAKKQEDKA RWLQACADER RRVQEDKEMG MEISENQKKL AMLNAQKAGH GKSKGYNRCP VAPPHQGLHP IHQRHITMPT SVPQQQVFGL AEPKRKSSLF WHTFNRLTPF RK
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