Centrosomal protein 20 (CEP20)

About Centrosomal protein 20

Centrosomal protein 20 (CEP20) is a protein from Homo sapiens identified by UniProt accession Q96NB1, 174 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	Centrosomal protein 20
UniProt accession	Q96NB1
Gene	CEP20
Organism	Homo sapiens
Length	174 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

multiple myeloma · score 0.21
overall survival · score 0.21
non-small cell lung carcinoma · score 0.07
PHF-tau measurement · score 0.06
neoplasm · score 0.05
hemorrhoid · score 0.03
mean corpuscular hemoglobin concentration · score 0.02
cancer · score 0.01
Miyoshi myopathy · score 0.01
carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96NB1-F1	alphafold	PREDICTED	73.74	—

Amino-acid sequence (174 residues)

MATVAELKAV LKDTLEKKGV LGHLKARIRA EVFNALDDDR EPRPSLSHEN LLINELIREY LEFNKYKYTA SVLIAESGQP VVPLDRQFLI HELNAFEESK DNTIPLLYGI LAHFLRGTKD GIQNAFLKGP SLQPSDPSLG RQPSRRKPMD DHLRKEEQKS TNIEDLHVSQ AVNR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards