About Sideroflexin-2
Sideroflexin-2 (SFXN2) is a protein
from Homo sapiens identified by UniProt accession
Q96NB2, 322 residues long.
MolForge cross-references it against 0 known binders and
71 disease associations.
Target properties
| Protein name | Sideroflexin-2 |
|---|
| UniProt accession | Q96NB2 |
|---|
| Gene | SFXN2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 322 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (71)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.29
- myeloid white cell count · score 0.26
- BMI-adjusted waist-hip ratio · score 0.25
- mean corpuscular hemoglobin concentration · score 0.21
- carotid plaque build · score 0.21
- smoking behavior · score 0.20
- mean corpuscular volume · score 0.18
- whole body water mass · score 0.13
- base metabolic rate measurement · score 0.11
- cigarettes per day measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96NB2-F1 | alphafold | PREDICTED | 85.01 | — |
Amino-acid sequence (322 residues)
MEADLSGFNI DAPRWDQRTF LGRVKHFLNI TDPRTVFVSE RELDWAKVMV EKSRMGVVPP GTQVEQLLYA KKLYDSAFHP DTGEKMNVIG RMSFQLPGGM IITGFMLQFY RTMPAVIFWQ WVNQSFNALV NYTNRNAASP TSVRQMALSY FTATTTAVAT AVGMNMLTKK APPLVGRWVP FAAVAAANCV NIPMMRQQEL IKGICVKDRN ENEIGHSRRA AAIGITQVVI SRITMSAPGM ILLPVIMERL EKLHFMQKVK VLHAPLQVML SGCFLIFMVP VACGLFPQKC ELPVSYLEPK LQDTIKAKYG ELEPYVYFNK GL
Explore Sideroflexin-2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets