Zinc finger protein 830 (ZNF830)

About Zinc finger protein 830

Zinc finger protein 830 (ZNF830) is a protein from Homo sapiens identified by UniProt accession Q96NB3, 372 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.

Target properties

Protein name	Zinc finger protein 830
UniProt accession	Q96NB3
Gene	ZNF830
Organism	Homo sapiens
Length	372 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (36)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.45
neuroinflammatory disorder · score 0.36
breast adenocarcinoma · score 0.18
age-related macular degeneration · score 0.07
X-linked retinal dysplasia · score 0.06
Familial exudative vitreoretinopathy · score 0.06
self reported educational attainment · score 0.06
retinitis pigmentosa · score 0.06
severe early-childhood-onset retinal dystrophy · score 0.05
Benign familial chorea · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96NB3-F1	alphafold	PREDICTED	65.59	—

Amino-acid sequence (372 residues)

MASSASARTP AGKRVINQEE LRRLMKEKQR LSTSRKRIES PFAKYNRLGQ LSCALCNTPV KSELLWQTHV LGKQHREKVA ELKGAKEASQ GSSASSAPHS VKRKAPDADD QDVKRAKATL VPQVQPSTSA WTTNFDKIGK EFIRATPSKP SGLSLLPDYE DEEEEEEEEE GDGERKRGDA SKPLSDAQGK EHSVSSSREV TSSVLPNDFF STNPPKAPII PHSGSIEKAE IHEKVVERRE NTAEALPEGF FDDPEVDARV RKVDAPKDQM DKEWDEFQKA MRQVNTISEA IVAEEDEEGR LDRQIGEIDE QIECYRRVEK LRNRQDEIKN KLKEILTIKE LQKKEEENAD SDDEGELQDL LSQDWRVKGA LL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards