About Zinc finger matrin-type protein 2
Zinc finger matrin-type protein 2 (ZMAT2) is a protein
from Homo sapiens identified by UniProt accession
Q96NC0, 199 residues long.
MolForge cross-references it against 0 known binders and
19 disease associations.
Target properties
| Protein name | Zinc finger matrin-type protein 2 |
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| UniProt accession | Q96NC0 |
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| Gene | ZMAT2 |
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| Organism | Homo sapiens |
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| Length | 199 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (19)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- systolic blood pressure · score 0.06
- monocyte count · score 0.04
- depressive symptom measurement · score 0.03
- forced expiratory volume · score 0.03
- body mass index · score 0.03
- bipolar I disorder · score 0.03
- unipolar depression · score 0.03
- aspartate aminotransferase measurement · score 0.02
- vital capacity · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96NC0-F1 | alphafold | PREDICTED | 71.74 | — |
Amino-acid sequence (199 residues)
MASGSGTKNL DFRRKWDKDE YEKLAEKRLT EEREKKDGKP VQPVKRELLR HRDYKVDLES KLGKTIVITK TTPQSEMGGY YCNVCDCVVK DSINFLDHIN GKKHQRNLGM SMRVERSTLD QVKKRFEVNK KKMEEKQKDY DFEERMKELR EEEEKAKAYK KEKQKEKKRR AEEDLTFEED DEMAAVMGFS GFGSTKKSY
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