Zinc finger protein 583 (ZNF583)

About Zinc finger protein 583

Zinc finger protein 583 (ZNF583) is a protein from Homo sapiens identified by UniProt accession Q96ND8, 569 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Zinc finger protein 583
UniProt accession	Q96ND8
Gene	ZNF583
Organism	Homo sapiens
Length	569 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

ulcerative colitis · score 0.14
neurodegenerative disease · score 0.05
cancer · score 0.04
neoplasm · score 0.01
dysplasia · score 0.00
glioblastoma · score 0.00
Chronic colitis · score 0.00
Sjogren syndrome · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96ND8-F1	alphafold	PREDICTED	71.98	—

Amino-acid sequence (569 residues)

MSKDLVTFGD VAVNFSQEEW EWLNPAQRNL YRKVMLENYR SLVSLGVSVS KPDVISLLEQ GKEPWMVKKE GTRGPCPDWE YVFKNSEFSS KQETYEESSK VVTVGARHLS YSLDYPSLRE DCQSEDWYKN QLGSQEVHLS QLIITHKEIL PEVQNKEYNK SWQTFHQDTI FDIQQSFPTK EKAHKHEPQK KSYRKKSVEM KHRKVYVEKK LLKCNDCEKV FNQSSSLTLH QRIHTGEKPY ACVECGKTFS QSANLAQHKR IHTGEKPYEC KECRKAFSQN AHLAQHQRVH TGEKPYQCKE CKKAFSQIAH LTQHQRVHTG ERPFECIECG KAFSNGSFLA QHQRIHTGEK PYVCNVCGKA FSHRGYLIVH QRIHTGERPY ECKECRKAFS QYAHLAQHQR VHTGEKPYEC KVCRKAFSQI AYLDQHQRVH TGEKPYECIE CGKAFSNSSS LAQHQRSHTG EKPYMCKECR KTFSQNAGLA QHQRIHTGEK PYECNVCGKA FSYSGSLTLH QRIHTGERPY ECKDCRKSFR QRAHLAHHER IHTMESFLTL SSPSPSTSNQ LPRPVGFIS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards