About Outer dynein arm-docking complex subunit 4
Outer dynein arm-docking complex subunit 4 (ODAD4) is a protein
from Homo sapiens identified by UniProt accession
Q96NG3, 672 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Outer dynein arm-docking complex subunit 4 |
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| UniProt accession | Q96NG3 |
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| Gene | ODAD4 |
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| Organism | Homo sapiens |
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| Length | 672 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (29)
Diseases linked to this target (Open Targets).
- primary ciliary dyskinesia · score 0.63
- Heterotaxy · score 0.33
- genetic disorder · score 0.19
- blood protein measurement · score 0.11
- reticulocyte count · score 0.09
- mean corpuscular hemoglobin · score 0.09
- mean corpuscular volume · score 0.07
- pulse pressure measurement · score 0.06
- reticulocyte measurement · score 0.04
- Immature Reticulocyte Fraction Measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96NG3-F1 | alphafold | PREDICTED | 71.92 | — |
Amino-acid sequence (672 residues)
MSDPEGETLR STFPSYMAEG ERLYLCGEFS KAAQSFSNAL YLQDGDKNCL VARSKCFLKM GDLERSLKDA EASLQSDPAF CKGILQKAET LYTMGDFEFA LVFYHRGYKL RPDREFRVGI QKAQEAINNS VGSPSSIKLE NKGDLSFLSK QAENIKAQQK PQPMKHLLHP TKGEPKWKAS LKSEKTVRQL LGELYVDKEY LEKLLLDEDL IKGTMKGGLT VEDLIMTGIN YLDTHSNFWR QQKPIYARER DRKLMQEKWL RDHKRRPSQT AHYILKSLED IDMLLTSGSA EGSLQKAEKV LKKVLEWNKE EVPNKDELVG NLYSCIGNAQ IELGQMEAAL QSHRKDLEIA KEYDLPDAKS RALDNIGRVF ARVGKFQQAI DTWEEKIPLA KTTLEKTWLF HEIGRCYLEL DQAWQAQNYG EKSQQCAEEE GDIEWQLNAS VLVAQAQVKL RDFESAVNNF EKALERAKLV HNNEAQQAII SALDDANKGI IRELRKTNYV ENLKEKSEGE ASLYEDRIIT REKDMRRVRD EPEKVVKQWD HSEDEKETDE DDEAFGEALQ SPASGKQSVE AGKARSDLGA VAKGLSGELG TRSGETGRKL LEAGRRESRE IYRRPSGELE QRLSGEFSRQ EPEELKKLSE VGRREPEELG KTQFGEIGET KKTGNEMEKE YE
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