Zinc finger protein 582 (ZNF582)

About Zinc finger protein 582

Zinc finger protein 582 (ZNF582) is a protein from Homo sapiens identified by UniProt accession Q96NG8, 517 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.

Target properties

Protein name	Zinc finger protein 582
UniProt accession	Q96NG8
Gene	ZNF582
Organism	Homo sapiens
Length	517 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (35)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.21
nonpapillary renal cell carcinoma · score 0.09
neoplasm · score 0.08
esophageal squamous cell carcinoma · score 0.06
cancer · score 0.04
oral squamous cell carcinoma · score 0.03
ulcerative colitis · score 0.03
infect · score 0.03
infection · score 0.03
dysplasia · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96NG8-F1	alphafold	PREDICTED	63.23	—

Amino-acid sequence (517 residues)

MSLGSELFRD VAIVFSQEEW QWLAPAQRDL YRDVMLETYS NLVSLGLAVS KPDVISFLEQ GKEPWMVERV VSGGLCPVLE SRYDTKELFP KQHVYEVESP QWEIMESLTS YGLECSSFQD DWECRNQFDR QQGNPDRHFH QMIIRHEEMP TFDQHASLTF YQKIHTREKP FGYNKCRKDF WQKELLINHQ GIYTNEKPYK CKECGKAFKY GSRLIQHENI HSGKKPYECK ECGKAFNSGS NFIQHQRVHT GEKPYECKDC EKAFSRSSQL IEHQRTHTGE KPYQCKECGK AFNRISHLKV HYRIHTGEKP YACKECGKTF SHRSQLIQHQ TVHTGRKLYE CKECGKAFNQ GSTLIRHQRI HTGEKPYECK VCGKAFRVSS QLKQHQRIHT GEKPYQCKVC GRAFKRVSHL TVHYRIHTGE KPYECKECGK AFSHCSQLIH HQVIHTEKKP YEYKECEKTL SHDSTTVQPQ RMHNRETHVN IINVEKPSIS SYPLLIIREF MLASNHMNGS NGESPLA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards