Zinc finger protein 3 homolog (ZFP3)

About Zinc finger protein 3 homolog

Zinc finger protein 3 homolog (ZFP3) is a protein from Homo sapiens identified by UniProt accession Q96NJ6, 502 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein name	Zinc finger protein 3 homolog
UniProt accession	Q96NJ6
Gene	ZFP3
Organism	Homo sapiens
Length	502 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (19)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.30
family history of Alzheimer’s disease · score 0.22
lymphocyte count · score 0.18
late-onset Alzheimers disease · score 0.08
Alzheimer disease · score 0.03
mean platelet volume · score 0.02
Down syndrome · score 0.02
body height · score 0.02
platelet component distribution width · score 0.02
hematocrit · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96NJ6-F1	alphafold	PREDICTED	74.44	—

Amino-acid sequence (502 residues)

MGTENKEVIP KEEISEESEP HGSLLEKFPK VVYQGHEFGA GCEEDMLEGH SRESMEEVIE QMSPQERDFP SGLMIFKKSP SSEKDRENNE SERGCSPSPN LVTHQGDTTE GVSAFATSGQ NFLEILESNK TQRSSVGEKP HTCKECGKAF NQNSHLIQHM RVHSGEKPFE CKECGKTFGT NSSLRRHLRI HAGEKPFACN ECGKAFIQSS HLIHHHRIHT GERPYKCEEC GKAFSQNSAL ILHQRIHTGE KPYECNECGK TFRVSSQLIQ HQRIHTEERY HECNECGKAF KHSSGLIRHQ KIHTGEKPYL CNECGKGFGQ SSELIRHQRI HTGDKPYECN ECGKTFGQNS EIIRHIRIHT GEKPYVCKEC GKAFRGNSEL LRHERIHTGE KPYECFECGK AFRRTSHLIV HQRIHTGEKP HQCNECARTF WDNSELLLHQ KIHIGEKPYE CSECEKTFSQ HSQLIIHQRI HTGEKPYECQ ECQKTFSRSS HLLRHQSVHC ME

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards