Serpin B11 (SERPINB11)

About Serpin B11

Serpin B11 (SERPINB11) is a protein from Homo sapiens identified by UniProt accession Q96P15, 392 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.

Target properties

Protein name	Serpin B11
UniProt accession	Q96P15
Gene	SERPINB11
Organism	Homo sapiens
Length	392 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (50)

Diseases linked to this target (Open Targets).

vitamin D measurement · score 0.50
protein measurement · score 0.41
genetic disorder · score 0.12
Barrett's esophagus · score 0.04
esophageal adenocarcinoma · score 0.04
eosinophil count · score 0.03
monocyte count · score 0.03
basophil count · score 0.03
platelet count · score 0.03
oral squamous cell carcinoma · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96P15-F1	alphafold	PREDICTED	89.41	—

Amino-acid sequence (392 residues)

MGSLSTANVE FCLDVFKELN SNNIGDNIFF SSLSLLYALS MVLLGARGET EEQLEKVLHF SHTVDSLKPG FKDSPKCSQA GRIHSEFGVE FSQINQPDSN CTLSIANRLY GTKTMAFHQQ YLSCSEKWYQ ARLQTVDFEQ STEETRKTIN AWVENKTNGK VANLFGKSTI DPSSVMVLVN AIYFKGQWQN KFQVRETVKS PFQLSEGKNV TVEMMYQIGT FKLAFVKEPQ MQVLELPYVN NKLSMIILLP VGIANLKQIE KQLNSGTFHE WTSSSNMMER EVEVHLPRFK LETKYELNSL LKSLGVTDLF NQVKADLSGM SPTKGLYLSK AIHKSYLDVS EEGTEAAAAT GDSIAVKSLP MRAQFKANHP FLFFIRHTHT NTILFCGKLA SP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards