WD repeat and FYVE domain-containing protein 2 (WDFY2)

About WD repeat and FYVE domain-containing protein 2

WD repeat and FYVE domain-containing protein 2 (WDFY2) is a protein from Homo sapiens identified by UniProt accession Q96P53, 400 residues long. MolForge cross-references it against 0 known binders and 133 disease associations.

Target properties

Protein name	WD repeat and FYVE domain-containing protein 2
UniProt accession	Q96P53
Gene	WDFY2
Organism	Homo sapiens
Length	400 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96P53-F1	alphafold	PREDICTED	94.23	—

Amino-acid sequence (400 residues)

MAAEIQPKPL TRKPILLQRM EGSQEVVNMA VIVPKEEGVI SVSEDRTVRV WLKRDSGQYW PSVYHAMPSP CSCMSFNPET RRLSIGLDNG TISEFILSED YNKMTPVKNY QAHQSRVTMI LFVLELEWVL STGQDKQFAW HCSESGQRLG GYRTSAVASG LQFDVETRHV FIGDHSGQVT ILKLEQENCT LVTTFRGHTG GVTALCWDPV QRVLFSGSSD HSVIMWDIGG RKGTAIELQG HNDRVQALSY AQHTRQLISC GGDGGIVVWN MDVERQETPE WLDSDSCQKC DQPFFWNFKQ MWDSKKIGLR QHHCRKCGKA VCGKCSSKRS SIPLMGFEFE VRVCDSCHEA ITDEERAPTA TFHDSKHNIV HVHFDATRGW LLTSGTDKVI KLWDMTPVVS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards