N-terminal EF-hand calcium-binding protein 3 (NECAB3)

About N-terminal EF-hand calcium-binding protein 3

N-terminal EF-hand calcium-binding protein 3 (NECAB3) is a protein from Homo sapiens identified by UniProt accession Q96P71, 396 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.

Target properties

Protein name	N-terminal EF-hand calcium-binding protein 3
UniProt accession	Q96P71
Gene	NECAB3
Organism	Homo sapiens
Length	396 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96P71-F1	alphafold	PREDICTED	70.81	—

Amino-acid sequence (396 residues)

MACAGLLTVC LLRPPAPQPQ PQTPRHPQLA PDPGPAGHTL FQDVFRRADK NDDGKLSFEE FQNYFADGVL SLGELQELFS GIDGHLTDNL ETEKLCDYFS EHLGVYRPVL AALESLNRAV LAAMDATKLE YERASKVDQF VTRFLLRETV SQLQALQSSL EGASDTLEAQ AHGWRSDAES VEAQSRLCGS RRAGRRALRS VSRSSTWSPG SSDTGRSSEA EMQWRLQVNR LQELIDQLEC KVRAVGPGPH KGGPSWYPPE PGPCWRPGPH SVPSQAPRLE PLREEDLAKG PDLHILMAQR QVQVAEEGLQ DFHRALRCYV DFTGAQSHCL HVSAQKMLDG ASFTLYEFWQ DEASWRRHQQ SPGSKAFQRI LIDHLRAPDT LTTVFFPASW WIMNNN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards