About Leucine-rich repeat-containing protein 3B
Leucine-rich repeat-containing protein 3B (LRRC3B) is a protein
from Homo sapiens identified by UniProt accession
Q96PB8, 259 residues long.
MolForge cross-references it against 0 known binders and
51 disease associations.
Target properties
| Protein name | Leucine-rich repeat-containing protein 3B |
|---|
| UniProt accession | Q96PB8 |
|---|
| Gene | LRRC3B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 259 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (51)
Diseases linked to this target (Open Targets).
- asthma · score 0.24
- alcohol drinking · score 0.14
- gut microbiome measurement · score 0.10
- neoplasm · score 0.08
- breast cancer · score 0.07
- cancer · score 0.07
- systolic blood pressure · score 0.05
- atypical teratoid rhabdoid tumor · score 0.04
- longevity · score 0.04
- medulloblastoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96PB8-F1 | alphafold | PREDICTED | 85.82 | — |
Amino-acid sequence (259 residues)
MNLVDLWLTR SLSMCLLLQS FVLMILCFHS ASMCPKGCLC SSSGGLNVTC SNANLKEIPR DLPPETVLLY LDSNQITSIP NEIFKDLHQL RVLNLSKNGI EFIDEHAFKG VAETLQTLDL SDNRIQSVHK NAFNNLKARA RIANNPWHCD CTLQQVLRSM ASNHETAHNV ICKTSVLDEH AGRPFLNAAN DADLCNLPKK TTDYAMLVTM FGWFTMVISY VVYYVRQNQE DARRHLEYLK SLPSRQKKAD EPDDISTVV
Explore Leucine-rich repeat-containing protein 3B with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets