Inositol hexakisphosphate kinase 3 (IP6K3)

About Inositol hexakisphosphate kinase 3

Inositol hexakisphosphate kinase 3 (IP6K3) is a protein from Homo sapiens identified by UniProt accession Q96PC2, 410 residues long. MolForge cross-references it against 0 known binders and 100 disease associations.

Target properties

Protein name	Inositol hexakisphosphate kinase 3
UniProt accession	Q96PC2
Gene	IP6K3
Organism	Homo sapiens
Length	410 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (100)

Diseases linked to this target (Open Targets).

platelet count · score 0.35
forced expiratory volume · score 0.32
blood phosphate measurement · score 0.32
celiac disease · score 0.30
phosphorus measurement · score 0.28
platelet crit · score 0.27
self reported educational attainment · score 0.26
neutrophil count · score 0.25
Malabsorption · score 0.24
myeloid white cell count · score 0.24

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96PC2-F1	alphafold	PREDICTED	75.39	—

Amino-acid sequence (410 residues)

MVVQNSADAG DMRAGVQLEP FLHQVGGHMS VMKYDEHTVC KPLVSREQRF YESLPLAMKR FTPQYKGTVT VHLWKDSTGH LSLVANPVKE SQEPFKVSTE SAAVAIWQTL QQTTGSNGSD CTLAQWPHAQ LARSPKESPA KALLRSEPHL NTPAFSLVED TNGNQVERKS FNPWGLQCHQ AHLTRLCSEY PENKRHRFLL LENVVSQYTH PCVLDLKMGT RQHGDDASEE KKARHMRKCA QSTSACLGVR ICGMQVYQTD KKYFLCKDKY YGRKLSVEGF RQALYQFLHN GSHLRRELLE PILHQLRALL SVIRSQSSYR FYSSSLLVIY DGQEPPERAP GSPHPHEAPQ AAHGSSPGGL TKVDIRMIDF AHTTYKGYWN EHTTYDGPDP GYIFGLENLI RILQDIQEGE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards