AP-1 complex subunit sigma-3 (AP1S3)

About AP-1 complex subunit sigma-3

AP-1 complex subunit sigma-3 (AP1S3) is a protein from Homo sapiens identified by UniProt accession Q96PC3, 154 residues long. MolForge cross-references it against 0 known binders and 83 disease associations.

Target properties

Protein name	AP-1 complex subunit sigma-3
UniProt accession	Q96PC3
Gene	AP1S3
Organism	Homo sapiens
Length	154 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96PC3-F1	alphafold	PREDICTED	93.40	—

Amino-acid sequence (154 residues)

MIHFILLFSR QGKLRLQKWY ITLPDKERKK ITREIVQIIL SRGHRTSSFV DWKELKLVYK RYASLYFCCA IENQDNELLT LEIVHRYVEL LDKYFGNVCE LDIIFNFEKA YFILDEFIIG GEIQETSKKI AVKAIEDSDM LQEVSTVSQT MGER

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards