Opalin (OPALIN)

About Opalin

Opalin (OPALIN) is a protein from Homo sapiens identified by UniProt accession Q96PE5, 141 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.

Target properties

Protein name	Opalin
UniProt accession	Q96PE5
Gene	OPALIN
Organism	Homo sapiens
Length	141 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (35)

Diseases linked to this target (Open Targets).

drug use measurement · score 0.13
gut microbiome measurement · score 0.10
glioblastoma multiforme · score 0.08
Abnormal delivery · score 0.06
central nervous system cancer · score 0.03
myeloid sarcoma · score 0.03
astrocytoma · score 0.02
ependymoma · score 0.02
oligodendroglioma · score 0.02
alkaline phosphatase measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96PE5-F1	alphafold	PREDICTED	62.45	—

Amino-acid sequence (141 residues)

MSFSLNFTLP ANTTSSPVTG GKETDCGPSL GLAAGIPLLV ATALLVALLF TLIHRRRSSI EAMEESDRPC EISEIDDNPK ISENPRRSPT HEKNTMGAQE AHIYVKTVAG SEEPVHDRYR PTIEMERRRG LWWLVPRLSL E

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards