Zinc finger imprinted 3 (ZIM3)

About Zinc finger imprinted 3

Zinc finger imprinted 3 (ZIM3) is a protein from Homo sapiens identified by UniProt accession Q96PE6, 472 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein name	Zinc finger imprinted 3
UniProt accession	Q96PE6
Gene	ZIM3
Organism	Homo sapiens
Length	472 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (12)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.17
IGF-1 measurement · score 0.09
gut microbiome measurement · score 0.08
triglyceride measurement · score 0.07
high density lipoprotein cholesterol measurement · score 0.07
osteosarcoma · score 0.02
appendicular lean mass · score 0.02
neoplasm · score 0.00
Duodenal Adenocarcinoma · score 0.00
T-cell acute lymphoblastic leukemia · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96PE6-F1	alphafold	PREDICTED	75.18	—

Amino-acid sequence (472 residues)

MNNSQGRVTF EDVTVNFTQG EWQRLNPEQR NLYRDVMLEN YSNLVSVGQG ETTKPDVILR LEQGKEPWLE EEEVLGSGRA EKNGDIGGQI WKPKDVKESL AREVPSINKE TLTTQKGVEC DGSKKILPLG IDDVSSLQHY VQNNSHDDNG YRKLVGNNPS KFVGQQLKCN ACRKLFSSKS RLQSHLRRHA CQKPFECHSC GRAFGEKWKL DKHQKTHAEE RPYKCENCGN AYKQKSNLFQ HQKMHTKEKP YQCKTCGKAF SWKSSCINHE KIHNAKKSYQ CNECEKSFRQ NSTLIQHKKV HTGQKPFQCT DCGKAFIYKS DLVKHQRIHT GEKPYKCSIC EKAFSQKSNV IDHEKIHTGK RAYECDLCGN TFIQKKNLIQ HKKIHTGEKP YECNRCGKAF FQKSNLHSHQ KTHSGERTYR CSECGKTFIR KLNLSLHKKT HTGQKPYGCS ECGKAFADRS YLVRHQKRIH SR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards