About Methylmalonyl-CoA epimerase, mitochondrial
Methylmalonyl-CoA epimerase, mitochondrial (MCEE) is a protein
from Homo sapiens identified by UniProt accession
Q96PE7, 176 residues long.
MolForge cross-references it against 0 known binders and
38 disease associations.
Target properties
| Protein name | Methylmalonyl-CoA epimerase, mitochondrial |
|---|
| UniProt accession | Q96PE7 |
|---|
| Gene | MCEE |
|---|
| Organism | Homo sapiens |
|---|
| Length | 176 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (38)
Diseases linked to this target (Open Targets).
- methylmalonic acidemia due to methylmalonyl-CoA epimerase deficiency · score 0.73
- genetic disorder · score 0.41
- methylmalonic acidemia · score 0.37
- PHF-tau measurement · score 0.26
- N-acetyl-D-glucosamine kinase measurement · score 0.22
- emotional symptom measurement · score 0.17
- eosinophil count · score 0.07
- eosinophil percentage of leukocytes · score 0.06
- glucuronate measurement · score 0.04
- blood protein measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96PE7-F1 | alphafold | PREDICTED | 86.85 | — |
Amino-acid sequence (176 residues)
MARVLKAAAA NAVGLFSRLQ APIPTVRASS TSQPLDQVTG SVWNLGRLNH VAIAVPDLEK AAAFYKNILG AQVSEAVPLP EHGVSVVFVN LGNTKMELLH PLGRDSPIAG FLQKNKAGGM HHICIEVDNI NAAVMDLKKK KIRSLSEEVK IGAHGKPVIF LHPKDCGGVL VELEQA
Explore Methylmalonyl-CoA epimerase, mitochondrial with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets