Membrane-spanning 4-domains subfamily A member 10…

About Membrane-spanning 4-domains subfamily A member 10

Membrane-spanning 4-domains subfamily A member 10 (MS4A10) is a protein from Homo sapiens identified by UniProt accession Q96PG2, 267 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Membrane-spanning 4-domains subfamily A member 10
UniProt accession	Q96PG2
Gene	MS4A10
Organism	Homo sapiens
Length	267 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

Crohn's disease · score 0.06
sleep apnea measurement · score 0.03
platelet count · score 0.02
ulcerative colitis · score 0.02
gonorrhea · score 0.02
colorectal cancer · score 0.02
neoplasm · score 0.01
gastric cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96PG2-F1	alphafold	PREDICTED	69.60	—

Amino-acid sequence (267 residues)

MKAEATVIPS RCARGLPSWQ VLSPVQPWQT SAPQNTTQPK LLAPHQHEKS QKKSSLLKEL GAFHITIALL HLVFGGYLAS IVKNLHLVVL KSWYPFWGAA SFLISGILAI TMKTFSKTYL KMLCLMTNLI SLFCVLSGLF VISKDLFLES PFESPIWRMY PNSTVHIQRL ELALLCFTVL ELFLPVPTAV TAWRGDCPSA KNDDACLVPN TPLHLKGLPV EPPPSYQSVI QGDAQHKQHQ RLREVKQVAP DTWIVTDGAA IWTQTAN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Membrane-spanning 4-domains subfamily A member 10 (MS4A10)