Fc receptor-like protein 4 (FCRL4)

About Fc receptor-like protein 4

Fc receptor-like protein 4 (FCRL4) is a protein from Homo sapiens identified by UniProt accession Q96PJ5, 515 residues long. MolForge cross-references it against 0 known binders and 149 disease associations.

Target properties

Protein name	Fc receptor-like protein 4
UniProt accession	Q96PJ5
Gene	FCRL4
Organism	Homo sapiens
Length	515 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (149)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.40
hemangioblastoma · score 0.37
breast ductal adenocarcinoma · score 0.37
skin basal cell carcinoma · score 0.37
skin squamous cell carcinoma · score 0.37
lung carcinoma · score 0.37
nodular melanoma · score 0.37
cutaneous melanoma · score 0.37
carcinoma of liver and intrahepatic biliary tract · score 0.37
superficial spreading melanoma · score 0.37

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96PJ5-F1	alphafold	PREDICTED	77.90	—

Amino-acid sequence (515 residues)

MLLWASLLAF APVCGQSAAA HKPVISVHPP WTTFFKGERV TLTCNGFQFY ATEKTTWYHR HYWGEKLTLT PGNTLEVRES GLYRCQARGS PRSNPVRLLF SSDSLILQAP YSVFEGDTLV LRCHRRRKEK LTAVKYTWNG NILSISNKSW DLLIPQASSN NNGNYRCIGY GDENDVFRSN FKIIKIQELF PHPELKATDS QPTEGNSVNL SCETQLPPER SDTPLHFNFF RDGEVILSDW STYPELQLPT VWRENSGSYW CGAETVRGNI HKHSPSLQIH VQRIPVSGVL LETQPSGGQA VEGEMLVLVC SVAEGTGDTT FSWHREDMQE SLGRKTQRSL RAELELPAIR QSHAGGYYCT ADNSYGPVQS MVLNVTVRET PGNRDGLVAA GATGGLLSAL LLAVALLFHC WRRRKSGVGF LGDETRLPPA PGPGESSHSI CPAQVELQSL YVDVHPKKGD LVYSEIQTTQ LGEEEEANTS RTLLEDKDVS VVYSEVKTQH PDNSAGKISS KDEES

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards