Beta-tectorin (TECTB)

About Beta-tectorin

Beta-tectorin (TECTB) is a protein from Homo sapiens identified by UniProt accession Q96PL2, 329 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.

Target properties

Protein name	Beta-tectorin
UniProt accession	Q96PL2
Gene	TECTB
Organism	Homo sapiens
Length	329 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (51)

Diseases linked to this target (Open Targets).

total cholesterol measurement · score 0.41
high density lipoprotein cholesterol measurement · score 0.41
protein measurement · score 0.33
alkaline phosphatase measurement · score 0.29
apolipoprotein A 1 measurement · score 0.29
serum alanine aminotransferase measurement · score 0.26
neurodegenerative disease · score 0.25
mean platelet volume · score 0.24
aspartate aminotransferase to alanine aminotransferase ratio · score 0.23
pancreatic adenocarcinoma · score 0.21

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96PL2-F1	alphafold	PREDICTED	67.92	—

Amino-acid sequence (329 residues)

MVTKAFVLLA IFAEASAKSC APNKADVILV FCYPKTIITK IPECPYGWEV HQLALGGLCY NGVHEGGYYQ FVIPDLSPKN KSYCGTQSEY KPPIYHFYSH IVSNDTTVIV KNQPVNYSFS CTYHSTYLVN QAAFDQRVAT VHVKNGSMGT FESQLSLNFY TNAKFSIKKE APFVLEASEI GSDLFAGVEA KGLSIRFKVV LNSCWATPSA DFMYPLQWQL INKGCPTDET VLVHENGRDH RATFQFNAFR FQNIPKLSKV WLHCETFICD SEKLSCPVTC DKRKRLLRDQ TGGVLVVELS LRSRGFSSLY SFSDVLHHLI MMLGICAVL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards