About RING finger and CHY zinc finger domain-containing protein 1
RING finger and CHY zinc finger domain-containing protein 1 (RCHY1) is a protein
from Homo sapiens identified by UniProt accession
Q96PM5, 261 residues long.
MolForge cross-references it against 0 known binders and
65 disease associations.
Target properties
| Protein name | RING finger and CHY zinc finger domain-containing protein 1 |
|---|
| UniProt accession | Q96PM5 |
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| Gene | RCHY1 |
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| Organism | Homo sapiens |
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| Length | 261 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (65)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.23
- platelet count · score 0.20
- FEV/FVC ratio · score 0.13
- self reported educational attainment · score 0.11
- Miyoshi myopathy · score 0.08
- oral squamous cell carcinoma · score 0.05
- hepatocellular carcinoma · score 0.04
- cancer · score 0.04
- multiple myeloma · score 0.04
- calcium measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96PM5-F1 | alphafold | PREDICTED | 90.16 | — |
Amino-acid sequence (261 residues)
MAATAREDGA SGQERGQRGC EHYDRGCLLK APCCDKLYTC RLCHDNNEDH QLDRFKVKEV QCINCEKIQH AQQTCEECST LFGEYYCDIC HLFDKDKKQY HCENCGICRI GPKEDFFHCL KCNLCLAMNL QGRHKCIENV SRQNCPICLE DIHTSRVVAH VLPCGHLLHR TCYEEMLKEG YRCPLCMHSA LDMTRYWRQL DDEVAQTPMP SEYQNMTVDI LCNDCNGRST VQFHILGMKC KICESYNTAQ AGGRRISLDQ Q
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