About FANCD2 opposite strand protein
FANCD2 opposite strand protein (FANCD2OS) is a protein
from Homo sapiens identified by UniProt accession
Q96PS1, 177 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | FANCD2 opposite strand protein |
|---|
| UniProt accession | Q96PS1 |
|---|
| Gene | FANCD2OS |
|---|
| Organism | Homo sapiens |
|---|
| Length | 177 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (16)
Diseases linked to this target (Open Targets).
- Fanconi anemia · score 0.57
- Fanconi anemia complementation group D2 · score 0.56
- genetic disorder · score 0.41
- ovarian cancer · score 0.27
- body height · score 0.25
- Hereditary breast and ovarian cancer syndrome · score 0.15
- hereditary breast ovarian cancer syndrome · score 0.15
- Fanconi anemia complementation group A · score 0.15
- Cleft palate · score 0.12
- Intellectual disability · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96PS1-F1 | alphafold | PREDICTED | 61.11 | — |
Amino-acid sequence (177 residues)
MAGYQLWSPW TPLDESFQWL RHTTPTPSSK HPFKASPCFP HTPSDLEVQL CFQEVTLVLD SPFLESGVSP KLPCHTSELR TMNNKGLVRK PQPIRLSGVD SVFGRVITAQ PPKWTGTFRV SDKSAFCKII SREHQWPIGL KEPQIQMTVT MCKQMLRSIL LLYATYKKCT FALQHSK
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