Aquaporin-10 (AQP10)

About Aquaporin-10

Aquaporin-10 (AQP10) is a protein from Homo sapiens identified by UniProt accession Q96PS8, 301 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.

Target properties

Protein name	Aquaporin-10
UniProt accession	Q96PS8
Gene	AQP10
Organism	Homo sapiens
Length	301 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (46)

Diseases linked to this target (Open Targets).

Red cell distribution width · score 0.37
type 2 diabetes mellitus · score 0.28
interleukin 6 receptor subunit alpha measurement · score 0.23
Drugs used in diabetes use measurement · score 0.20
mean corpuscular hemoglobin concentration · score 0.17
mean corpuscular hemoglobin · score 0.12
mean corpuscular volume · score 0.08
red blood cell density measurement · score 0.06
smoking initiation · score 0.03
juvenile idiopathic arthritis · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96PS8-F1	alphafold	PREDICTED	91.26	—

Amino-acid sequence (301 residues)

MVFTQAPAEI MGHLRIRSLL ARQCLAEFLG VFVLMLLTQG AVAQAVTSGE TKGNFFTMFL AGSLAVTIAI YVGGNVSGAH LNPAFSLAMC IVGRLPWVKL PIYILVQLLS AFCASGATYV LYHDALQNYT GGNLTVTGPK ETASIFATYP APYLSLNNGF LDQVLGTGML IVGLLAILDR RNKGVPAGLE PVVVGMLILA LGLSMGANCG IPLNPARDLG PRLFTYVAGW GPEVFSAGNG WWWVPVVAPL VGATVGTATY QLLVALHHPE GPEPAQDLVS AQHKASELET PASAQMLECK L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards