Ciliary microtubule associated protein 1A (CIMAP1A)

About Ciliary microtubule associated protein 1A

Ciliary microtubule associated protein 1A (CIMAP1A) is a protein from Homo sapiens identified by UniProt accession Q96PU9, 254 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.

Target properties

Protein name	Ciliary microtubule associated protein 1A
UniProt accession	Q96PU9
Gene	CIMAP1A
Organism	Homo sapiens
Length	254 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (34)

Diseases linked to this target (Open Targets).

platelet count · score 0.34
benign prostatic hyperplasia · score 0.33
lower urinary tract symptom · score 0.33
mean platelet volume · score 0.32
body height · score 0.26
platelet crit · score 0.25
lymphocyte count · score 0.21
platelet component distribution width · score 0.20
platelet-to-lymphocyte ratio · score 0.20
Red cell distribution width · score 0.17

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96PU9-F1	alphafold	PREDICTED	74.23	—

Amino-acid sequence (254 residues)

MTEEVWMGTW RPHRPRGPIM ALYSSPGPKY LIPPTTGFMK HTPTKLRAPA YSFRGAPMLL AENCSPGPRY NVNPKILRTG KDLGPAYSIL GRYQTKTMLT PGPGDYFPEK STKYVFDSAP SHSISARTKA FRVDSTPGPA AYMLPMVMGP NTVGKASQPS FSIKGRSKLG GFSDDLHKTP GPAAYRQTDV RVTKFKAPQY TMAARVEPPG DKTLKPGPGA HSPEKVTLTK PCAPVVTFGI KHSDYMTPLL VDVE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards