About BTB/POZ domain-containing protein 9
BTB/POZ domain-containing protein 9 (BTBD9) is a protein
from Homo sapiens identified by UniProt accession
Q96Q07, 612 residues long.
MolForge cross-references it against 0 known binders and
52 disease associations.
Target properties
| Protein name | BTB/POZ domain-containing protein 9 |
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| UniProt accession | Q96Q07 |
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| Gene | BTBD9 |
|---|
| Organism | Homo sapiens |
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| Length | 612 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (52)
Diseases linked to this target (Open Targets).
- restless legs syndrome · score 0.49
- insomnia measurement · score 0.37
- physical activity measurement · score 0.34
- chronotype measurement · score 0.34
- daytime rest measurement · score 0.28
- IGF-1 measurement · score 0.23
- insulin like growth factor measurement · score 0.22
- body mass index · score 0.21
- emotional symptom measurement · score 0.14
- self reported educational attainment · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96Q07-F1 | alphafold | PREDICTED | 88.16 | — |
Amino-acid sequence (612 residues)
MSNSHPLRPF TAVGEIDHVH ILSEHIGALL IGEEYGDVTF VVEKKRFPAH RVILAARCQY FRALLYGGMR ESQPEAEIPL QDTTAEAFTM LLKYIYTGRA TLTDEKEEVL LDFLSLAHKY GFPELEDSTS EYLCTILNIQ NVCMTFDVAS LYSLPKLTCM CCMFMDRNAQ EVLSSEGFLS LSKTALLNIV LRDSFAAPEK DIFLALLNWC KHNSKENHAE IMQAVRLPLM SLTELLNVVR PSGLLSPDAI LDAIKVRSES RDMDLNYRGM LIPEENIATM KYGAQVVKGE LKSALLDGDT QNYDLDHGFS RHPIDDDCRS GIEIKLGQPS IINHIRILLW DRDSRSYSYF IEVSMDELDW VRVIDHSQYL CRSWQKLYFP ARVCRYIRIV GTHNTVNKIF HIVAFECMFT NKTFTLEKGL IVPMENVATI ADCASVIEGV SRSRNALLNG DTKNYDWDSG YTCHQLGSGA IVVQLAQPYM IGSIRLLLWD CDDRSYSYYV EVSTNQQQWT MVADRTKVSC KSWQSVTFER QPASFIRIVG THNTANEVFH CVHFECPEQQ SSQKEENSEE SGTGDTSLAG QQLDSHALRA PSGSSLPSSP GSNSRSPNRQ HQ
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